Unicompartmental Knee Arthroplasty vs. High Tibial Osteotomy for Medial Knee Osteoarthritis (UNIKORN): a Study Protocol of a Randomized Controlled Trial

Töölö Hospital

Status: Not yet enrolling

Conditions: Knee Osteoarthritis

Treatments: Procedure: Unicompartmental knee arthroplasty; Procedure: High tibial osteotomy

Study type: Interventional

Funder types: Other

Identifiers

NCT05442242

HUS/1259/2019

Details and patient eligibility

About

Unicompartmental knee arthroplasty (UKA) and High Tibial Osteotomy are both valid treatment options for isolated medial knee osteoarthritis. Literature to date is lacking high grade evidence of the outcomes between these procedures. This is a study protocol for randomized controlled trial comparing UKA vs HTO in late stage medial knee osteoarthritis.

Enrollment: 100 estimated patients

Sex: All

Ages: 45 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Isolated KL 3-4 medial knee arthrosis
• Varus > 3 degrees
• Age 45-65 years

Exclusion criteria

• Post-traumatic arthrosis
• Arthrosis in the lateral compartment more than KL grade I in MRI
• Post- traumatic arthrosis
• Instability
• Malignancy Obesity

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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100 participants in 2 patient groups

Unicompartmental knee osteoarthritis

Active Comparator group

Treatment:

Procedure: Unicompartmental knee arthroplasty

High tibial osteotomy

Active Comparator group

Treatment:

Procedure: High tibial osteotomy