Unilateral Epidural Block Versus Ultrasound Guided Combined Femoro-sciatic Nerves Block for Patients With Low Ejection Fraction

Ain Shams University

Status: Not yet enrolling

Conditions: Fracture Tibia; Low Ejection Fraction Patients

Treatments: Procedure: unilateral epidural anesthesia; Procedure: Ultrasound guided femoro/ sciatic nerve block

Study type: Interventional

Funder types: Other

Identifiers

NCT05506501

OFT IRB00006379

Details and patient eligibility

About

compare unilateral epidural anesthesia versus femoral/sciatic nerve block by ultrasound guided as anesthetic technique for cases with low ejection fraction undergoing insertion of nail tibia for fixation of fracture shaft tibia.

Full description

Group A ;( Unilateral epidural anesthesia group) Forty patients with low ejection fraction (30-40%) will do elective insertion of nail tibia for fixation of fracture shaft tibia using unilateral epidural anesthesia.

Group B;;( Ultrasound guided femoro/ sciatic nerve block group) Forty patients with low ejection fraction (30-40%) will do elective insertion of nail tibia for fixation of fracture shaft tibia by femoral/sciatic nerve block using ultrasound guidance.

For each patient, onset of sensory and motor block, degree of motor block, sign of sensory block in the contralateral lower limb for the epidural group, success in providing adequate anesthesia, hemodynamic changes, time of first analgesic request will be recorded.

Enrollment: 80 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18 to 60 years old.
• Patients scheduled for elective insertion of nail tibia for fixation of fracture shaft tibia.
• Patients with low ejection fraction (30-40%).

Exclusion criteria

• Patient refusal
• Uncooperative patient
• Unconscious patients
• Cases with head trauma
• History of relevant drug allergy to local anesthetics
• Local infection at the site of the block
• Patients with coagulopathies and impaired platelet functions
• Patients with hemodynamic instability
• Previous neurological deficit in lower limb and previous femoral artery grafts or injuries.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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80 participants in 2 patient groups

Unilateral epidural anesthesia group

Active Comparator group

Description:

Forty patients with low ejection fraction (30-40%) will do elective insertion of nail tibia for fixation of fracture shaft tibia using unilateral epidural anesthesia.

Treatment:

Procedure: unilateral epidural anesthesia

Ultrasound guided femoro/ sciatic nerve block group

Active Comparator group

Description:

Forty patients with low ejection fraction (30-40%) will do elective insertion of nail tibia for fixation of fracture shaft tibia by femoral/sciatic nerve block using ultrasound guidance.

Treatment:

Procedure: Ultrasound guided femoro/ sciatic nerve block