Unripe Banana Peel Powder and Lemongrass Oil in Chronic Ulcer

Universidade do Vale do Sapucai

Status and phase: Completed; Phase 1

Conditions: Healing Ulcer; Chronic Ulcer

Treatments: Biological: Collagenase ointment; Biological: gel combined with lemongrass (Cymbopogon citratus) oil at 0.1% concentration; Biological: Gel with 10% peel powder of unripe banana

Study type: Interventional

Funder types: Other

Identifiers

NCT04963829

Banana peel

Details and patient eligibility

About

To evaluate the activity of a gel composed of 10% peel powder of unripe banana (Musa sapientum) combined with lemongrass (Cymbopogon citratus) oil, at 0.1% concentration, in patients with chronic ulcers.

Full description

Purpose: To evaluate the activity of a gel composed of 10% peel powder of unripe banana (Musa sapientum) combined with lemongrass (Cymbopogon citratus) oil, at 0.1% concentration, in patients with chronic ulcers. Methods: This is a clinical, individual, analytical, interventional, longitudinal, prospective, controlled study with convenience sampling. Three groups will be used, as follows: control group 1 (CG1) with 7 participants will be treated with collagenase, control group 2 (CG2) with 7 participants will be treated with a gel composed of 10% unripe banana peel powder, and study group (SG) with 11 patients will be treated with the abovementioned gel combined with lemongrass oil at 0.1% concentration. The ulcer areas will be analyzed once a week for 4 weeks. Afterward, wound areas will be measured and the obtained data will be subjected to statistical analysis.

Enrollment: 25 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• presence of chronic ulcers,
• 18 years of age and older

Exclusion criteria

• Patients who had any type of allergic reaction to the study products during treatment

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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25 participants in 3 patient groups

Study Group (SG)

Active Comparator group

Description:

Participants who used the abovementioned gel combined with lemongrass (Cymbopogon citratus) oil at 0.1% concentration.

Treatment:

Biological: gel combined with lemongrass (Cymbopogon citratus) oil at 0.1% concentration

Control Group 1 (CG1)

Active Comparator group

Description:

Participants who were subjected to a standardized treatment (collagenase ointment was selected for this treatment),

Treatment:

Biological: Collagenase ointment

Control Group 2 (CG2)

Active Comparator group

Description:

Participants who used a gel made of 10% peel powder of unripe banana (M. sapientum)

Treatment:

Biological: Gel with 10% peel powder of unripe banana