Upper Extremity Function, Shoulder Position Sense and Disability Level İn Patients With Multiple Sclerosis

Ankara Yildirim Beyazıt University

Status: Completed

Conditions: Upper Extremity Function; Position Sense; Physical Therapy

Treatments: Other: Upper extremity function; Other: Shoulder position sense

Study type: Interventional

Funder types: Other

Identifiers

NCT03846336

25

Details and patient eligibility

About

The purposes of this study is to investigate the relationship between upper extremity muscle function and shoulder position sense in patients with Multiple Sclerosis (MS) and which best projects the disability status.

Upper extremity dysfunction is considered to be the main cause of the loss performance of activities of daily living and this problem was include all motor and somatosensory components of function. Any failure in each of these components will likely create an impairment in the normal function.

One of the most important components of the somatosensory system is joint position sense, a sub-modality of proprioception. Position sense disorders are seen from the early stages of the disease and upper extremity function problems is experienced depending on position sense disorders in patients with MS.

Expanded Disability Status Scale (EDSS) is one of the most commonly outcome measures in evaluating the level of disability in MS population. Because EDSS scale emphasis on ambulation, so it is insensitive to upper extremity function. But the ability to use walking aids (e.g., canes, walkers, wheelchairs, etc.) may be affected by the UE impairment so shoulder position sense.

When literature is examined, there is no study which examines the relationship between upper extremity muscle function and shoulder position sense in patients with Multiple Sclerosis and which best projects the disability status. For all these reasons, we think that shoulder position sense is changed both dominant and non-dominant side during flexion and abduction movements in mild-moderate MS patients and that these deficits are correlated with upper extremity function and disability level.

Full description

This study was aimed to investigate the relationship between upper extremity muscle function and shoulder position sense in patients with MS and which best projects the disability status.

21 PwMS and 20 healthy volunteers with matching ages and genders were included the study. A neurologic examination was performed using the EDSS by a neurologist.

Upper extremity function was evaluated with 9-Hole Peg Test (9-HPT). Shoulder position sense was evaluated with Dualer IQTM digital inclinometer (J-TECH medical, Salt Lake City, UK, USA).

Enrollment: 41 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of Multiple Sclerosis Disease
• The level of disability should be between 0.5-4 according to EDSS

Exclusion criteria

• Patients with acute attacks (three months prior to the study)
• Mini-Mental State Examination (MMSE) score of less tahn 25 points
• History of shoulder injury, surgery, medical problems or other neurological disorders in any of the participants

Trial design

Primary purpose: Screening

Allocation: Non-Randomized

Interventional model: Factorial Assignment

Masking: None (Open label)

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41 participants in 2 patient groups

Multiple Sclerosis

Experimental group

Description:

Patients with confirmed diagnosis of clinically definite MS and physician-administered EDSS range of 1-3.5.

Treatment:

Other: Shoulder position sense

Other: Upper extremity function

Healthy individuals

Other group

Description:

20 healthy volunteers with matching ages and genders.

Treatment:

Other: Shoulder position sense

Other: Upper extremity function