Upper GI Outcomes Following EMR (UGI-EMR)

Professor Michael Bourke

Status: Completed

Conditions: Adenoma, Villous

Treatments: Procedure: Endoscopic Mucosal Resection

Study type: Observational

Funder types: Other

Identifiers

NCT02305290

HREC2014/7/4.6 (4033)

Details and patient eligibility

About

The purpose of this study is to evaluate the long-term outcomes of Endoscopic Resection (ER) of superficial lesions of the Upper Gastrointestinal Tract(UGIT)

Full description

Endoscopic resection (ER) of superficial lesions of the upper gastrointestinal tract is a safe and effective surgery-sparing modality in experienced hands. It is often curative of dysplastic lesions and is associated with minimal complications and high patient acceptance (1-5). Westmead Hospital has accumulated a significant amount of experience in the removal of such lesions; however, there is limited research to document the long term outcomes of patients undergoing endoscopic resection.The purpose of this study is to evaluate the long-term outcomes of ER of superficial lesions of the UGIT.

Enrollment: 200 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• UGIT lesion > 10mm
• Lesion limited to the mucosal and/or submucosal layer (T1 lesion)
• Aged 18 years or older

Exclusion criteria

• Lesion less than 10mm
• Gastric lesion involves the muscularis propria (T2 lesion) on other staging modalities such as endoscopic ultrasonography (EUS)
• Aged younger than 18 years

Trial design

200 participants in 1 patient group

Endoscopic Mucosal Resection

Description:

Patients who are referred for Endoscopic Mucosal Resection of Upper Gastrointestinal Lesions will be included in this cohort.

Treatment:

Procedure: Endoscopic Mucosal Resection