Upper Limb Muscle Strength Models for Patients With Motor Impairment. (MusMapS)

Pôle Saint Hélier

Status: Completed

Conditions: Spinal Cord Injuries; Stroke; Multiple Sclerosis

Treatments: Other: Upper limb isokinetic forces measurements

Study type: Interventional

Funder types: Other

Identifiers

NCT06608121

2024-A01007-40

Details and patient eligibility

About

Upper limb motor impairments are common. They affect quality of life and can lead to dependency. They are mainly due to neurological conditions such as stroke, multiple sclerosis, and traumatic spinal cord injury. However, the contractile properties of muscle, in particular the maximum force that can be generated voluntarily (MVF) depending on joint angle and motion speed, have been mainly studied and modeled in healthy people. This study aims at developing mathematical models describing residual muscle forces in patients with motor impairments. The knowledge could guide patients' rehabilitation and could be useful for the development of robotic assistance systems that use patients' residual capacities to control the level of assistance provided.

Enrollment: 32 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged between 18 and 85
• A patient who is a member or beneficiary of a social security scheme
• Patients hospitalised at the Saint-Hélier rehabilitation centre for a stroke more than 15 days old, MS or SCI
• Patients with a motor deficit ≤3/5 on the MRC (Medical Research Council) scale in both internal-external shoulder rotation and elbow flexion-extension.
• Patient with voluntary consent to participate in this study.

Exclusion criteria

• Spasticity >3/4 on the Aschworth scale in the shoulder abductor or elbow flexor muscles.
• Cognitive impairment that may interfere with measurements (MOCA < 20/30)
• Presence of a pressure sore > stage 2 at the ischial level
• Recent trauma to limbs or spine
• Decompensated heart disease or other unbalanced pathology which contraindicates or may hinder isokinetic testing.
• Persons deprived of their liberty by a judicial or administrative decision
• Pregnant women, women in labour or nursing mothers.

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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32 participants in 1 patient group

Experimental

Experimental group

Treatment:

Other: Upper limb isokinetic forces measurements