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Uremic Toxins and Outcomes in Chronic Kidney Disease

Shanghai Jiao Tong University logo

Shanghai Jiao Tong University

Status

Enrolling

Conditions

Chronic Kidney Diseases

Study type

Observational

Funder types

Other

Identifiers

NCT03711617
CKD-toxins

Details and patient eligibility

About

The aim of this cohort study is:

To investigate the etiology and epidemiology of comorbidities in CKD; To find out risk factors associated with the mortality of CKD; To find out uremic toxins which are related to the mortality and comorbidities of CKD; To focuse on the association between uremic toxins and inflammation, oxidative stress and nutritional status in CKD.

Full description

To investigate the etiology and epidemiology of comorbidities in CKD; To find out risk factors associated with the mortality of CKD; To find out uremic toxins which are related to the mortality and comorbidities of CKD; To focuse on the association between uremic toxins and inflammation, oxidative stress and nutritional status in CKD.

Enrollment

500 estimated patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • age ≥18 years old;
  • clinically diagnosed with chronic kidney disease, according K/DOQI criteria.

Exclusion criteria

  • acute kidney injury
  • history of kidney injury <3 months
  • malignancy
  • pregnancy
  • incomplete clinical data

Trial design

500 participants in 2 patient groups

CKD-ND
Description:
patients with non-dialysis CKD
CKD-MHD
Description:
patients with maintenance hemodialysis

Trial contacts and locations

1

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Central trial contact

Wenji Wang, MD; Feng Ding, PhD

Data sourced from clinicaltrials.gov

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