Uremic Toxins in the Intensive Care Unit (ICU): Patients With Sepsis

Ghent University Hospital (UZ)

Status: Withdrawn

Conditions: Multi Organ Failure; Renal Failure

Treatments: Procedure: Dialysis during 6 hours; Procedure: Dialysis during 8 hours; Procedure: Dialysis during 4 hours

Study type: Interventional

Funder types: Other

Identifiers

NCT00752245

2008/373

Details and patient eligibility

About

Study of the kinetics of uremic toxins in the ICU patients with acute renal failure, in order to optimize the dialysis dose: patients with sepsis/multi-organ failure. The sampling of blood and dialysate will be done during dialyses with different durations (4, 6 and 8h)

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• ICU patients with sepsis/multi-organ failure with acute renal failure

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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0 participants in 3 patient groups

1

Experimental group

Description:

Dialysis during 4 hours

Treatment:

Procedure: Dialysis during 4 hours

2

Active Comparator group

Description:

Dialysis during 6 hours

Treatment:

Procedure: Dialysis during 6 hours

3

Active Comparator group

Description:

Dialysis during 8 hours

Treatment:

Procedure: Dialysis during 8 hours