Uremic Toxins in the Intensive Care Units (ICU): Patients With Lactate Acidosis

Ghent University Hospital (UZ)

Status: Completed

Conditions: Acute Renal Failure

Treatments: Procedure: Dialysis during 8 hours; Procedure: Dialysis during 4 hours; Procedure: Dialysis during 6 hours

Study type: Interventional

Funder types: Other

Identifiers

NCT00752453

2008/375

Details and patient eligibility

About

Study of the kinetics of uremic toxins in the ICU patients with acute renal failure, in order to optimize the dialysis dose: patients with lactate acidosis. The sampling of blood and dialysate will be done during dialysis with different durations (4, 6 and 8 h)

Enrollment: 8 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Includes ICU patients with lactate acidosis with acute renal failure

Exclusion Criteria:

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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8 participants in 3 patient groups

1

Experimental group

Description:

Dialysis during 4 hours

Treatment:

Procedure: Dialysis during 4 hours

2

Experimental group

Description:

Dialysis during 6 hours

Treatment:

Procedure: Dialysis during 6 hours

3

Experimental group

Description:

Dialysis during 8 hours

Treatment:

Procedure: Dialysis during 8 hours