Ureteral Stenting After Retrograde Intrarenal Surgery for Renal Stones

Al-Azhar University

Status: Enrolling

Conditions: Ureteral Stent; Kidney Stone; Retrograde Intrarenal Surgery

Treatments: Procedure: Retrograde intrarenal surgery with external ureteral catheter; Procedure: Retrograde intrarenal surgery with double J internal ureteral stent

Study type: Interventional

Funder types: Other

Identifiers

NCT05738304

Uro_Azhar_11_023

Details and patient eligibility

About

Several studies evaluated the benefit of a short-term external ureteral catheter (UC) compared to double-J (DJ) ureteral stent after flexible ureteroscopy (URS); the results were controversial. These studies had combined analyses of ureteral and renal stones with a high risk of selection bias. Studies comparing external UC and DJ stent after flexible URS for isolated renal stones are lacking.

In the present study, the investigators will compare the outcomes of using a one-day external UC versus a DJ internal ureteral stent for ureteral drainage after retrograde flexible URS (retrograde intrarenal surgery "RIRS") for renal stones. The investigators aim to identify the best ureteral drainage method after RIRS regarding stone clearance, complications, and stent-related symptoms.

Enrollment: 250 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients of either gender in whom RIRS was the primary modality.

Exclusion criteria

• Pregnant women
• Active urinary tract infection
• solitary kidney
• Concomitant pathology that need intervention in the same setting
• Patients with surgical incidents that indicate double-J stenting (Residual sizable fragments, ureteral false passage, ureteral mucosal laceration, ureteral perforation, and calyceal rupture).

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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250 participants in 2 patient groups

External Ureteral Catheter group

Experimental group

Description:

After RIRS, an external ureteral catheter will be placed for one day.

Treatment:

Procedure: Retrograde intrarenal surgery with external ureteral catheter

Double J group

Active Comparator group

Description:

After RIRS, a double J internal ureteral stent will be placed for 2 weeks.

Treatment:

Procedure: Retrograde intrarenal surgery with double J internal ureteral stent