Ureteral Stents Versus Percutaneous Nephrostomy for Initial Urinary Drainage

Cairo University (CU)

Status: Completed

Conditions: Ureteric Stones; Obstructive Uropathy; Children; Acute Renal Failure

Treatments: Procedure: Definitive stone management; Procedure: bilateral double J ureteric stent; Procedure: percutaneous nephrostomy insertion

Study type: Interventional

Funder types: Other

Identifiers

NCT02055430

61177

Details and patient eligibility

About

To compare percutaneous nephrostomy (PCN) versus double J stent (JJ) as an initial urinary drainage in children

Full description

To compare percutaneous nephrostomy (PCN) versus double J stent (JJ) as an initial urinary drainage in children with obstructive calcular anuria and acute renal failure due to ureteric calculi to identify selection criteria for initial urinary drainage method to improve drainage, to decrease complications and to facilitate subsequent definitive clearance of stones as this comparison is lacking in literature

Enrollment: 90 patients

Sex: All

Ages: Under 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• children ≤12 years old presenting with Obstructive Anuria and Acute Renal Failure due to bilateral ureteric stones

Exclusion criteria

• Patients with grade 0-1 hydronephrosis
• fever, pyonephrosis or sepsis.
• any contraindication to both methods of drainage (urinary diversion, urethral stricture or uncontrolled coagulopathy).

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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90 participants in 2 patient groups

percutaneous nephrostomy

Active Comparator group

Description:

percutaneous nephrostomy insertion (6-8 Fr in size) for initial urinary drainage followed by definitive stone management.

Treatment:

Procedure: percutaneous nephrostomy insertion

Procedure: Definitive stone management

Bilateral double J ureteric stents

Active Comparator group

Description:

double J ureteric stent insertion (4.8-6 Fr JJ in size) for initial urinary drainage followed by definitive stone management.

Treatment:

Procedure: bilateral double J ureteric stent

Procedure: Definitive stone management