Urethral Vascularization and Urodynamics (UVASC)

Insel Gruppe AG, University Hospital Bern

Status: Invitation-only

Conditions: Vascularisation; Stress Urinary Incontinence; Urodynamic Exam; Ultrasound

Treatments: Diagnostic Test: 3D Ultrasound

Study type: Interventional

Funder types: Other

Identifiers

NCT07185698

2024-01776 (Other Identifier)

Details and patient eligibility

About

The urethra plays a crucial role in maintaining urinary continence. Its complex blood supply is still not well understood. Particularly in the context of urethral pressure. Urethral pressure can be measured by bladder and urethral pressure studies (urodynamic).

This study aims to use advanced imaging techniques to analyse the blood supply of the urethra and correlate it to urethral pressure measurements.

Elucidating these relationships will improve our understanding of urethral function and malfunction, and ultimately optimise diagnosis and treatment of stress urinary incontinence. A total of 35 participants with stress urinary incontinence and 35 without stress urinary incontinence will be asked to participate in this study.

Enrollment: 70 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Urodynamic examination
• Written informed consent
• Understanding of the German language
• Indicated urodynamic assessment
• Endovaginal and perineal ultrasound feasible

Exclusion criteria

• Urinary tract infections
• Transgender Population
• Pregnancy
• History of incontinence or prolapse surgery
• Pelvic prolapse higher than second degree
• Prior pelvic radiotherapy
• Prior history of gynecologic tumor

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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70 participants in 2 patient groups

Stress urinary incontinence

Experimental group

Description:

participants with stress urinary incontinence

Treatment:

Diagnostic Test: 3D Ultrasound

NO Stress Urinary Incontinence

Experimental group

Description:

Participants referred to urodynamics without stress urinary incontinence

Treatment:

Diagnostic Test: 3D Ultrasound