Urinary Antigen Test for Stretococcus Pneumoniae Serotype Prevalence in Community Acquired Pneumonia

The Chinese University of Hong Kong

Status: Enrolling

Conditions: Pneumonia

Treatments: Diagnostic Test: urinary kit for pneumococcus antigen assay

Study type: Observational

Funder types: Other

Identifiers

NCT05374018

CREC 2020.34

Details and patient eligibility

About

This is an epidemiology study for the prevalence and serotypes of pneumococcus pneumoniae in hospitalized patients with community acquired pneumonia (CAP). The serotypes of the pneumococcus pneumoniae will be determined by a urinary antigen assay

Enrollment: 1,800 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Admitted with signs and symptoms suggestive of pneumonia which include one or more of the followings:

1. fever
2. CXR changes with consolidation, increased alveolar shadowing or hazziness
3. respiratory symptoms like increase shortness of breath, cough with sputum Raised inflammatory markers suggesting of bacterial infection with either increased white cell count or C-reactive protein, or both

Exclusion criteria

• Nosocomial pneumonia which is acquired >= 48 hours after hospital admission. Pneumonia which are already known to be caused by pathogens other than pneumococcus pneumoniae.