Urinary Function and Multimorbidity Risks: A Longitudinal Study in Beijing Community-Dwelling Elderly (UFMR-BE)

Chinese PLA General Hospital (301 Hospital)

Status: Not yet enrolling

Conditions: Chronic Kidney Disease; Lower Urinary Tract Symptoms; Benign Prostatic Hyperplasia; Diabetes Mellitus; Cardiovascular Diseases; Female Pelvic Floor Dysfunction; Metabolic Syndrome; Overactive Bladder

Study type: Observational

Funder types: Other

Identifiers

NCT07357714

UFMR-BE

Details and patient eligibility

About

This study focuses on Beijing community residents aged 60 and above, aiming to understand how urinary function (like bladder or kidney function) and multiple health problems (such as high blood pressure, diabetes) affect each other as people age-since current studies often only look at single diseases and don't cover this group well. To join, participants need to be a 60+ Beijing community resident who can answer simple questions; those with serious mental illnesses or expected lifespan under 1 year can't take part. The study starts with a baseline check (asking about the participants' health, habits, doing blood/urine tests or urinary function assessments, and possibly collecting small blood/urine samples). After that, the investigators will follow up every 6-12 months (via phone or clinic to update health info) and repeat key checks yearly; people with lower cognitive ability will be checked every 3 months. The investigators will also record new illnesses, mobility issues (like falls), or death. The study has passed ethical review-participants will get clear info before joining, can quit anytime, and participants' data will stay private; participants will also get free health check reports and basic advice. For participants, this means regular health monitoring; for everyone, it'll help make tools to spot high-risk groups (like a community app), design better help (e.g., exercise plans), and push for yearly urinary health checks in communities.

Enrollment: 500 estimated patients

Sex: All

Ages: 60+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age ≥ 60 years
• Permanent resident of the participating Beijing community
• Able to cooperate with and complete study questionnaires and related procedures

Exclusion criteria

• Severe mental illness that impairs ability to cooperate with the study
• End-stage disease (confirmed by clinical diagnosis)
• Clinically assessed life expectancy < 1 year

Trial design

500 participants in 1 patient group

Beijing Community Elderly

Description:

This is a single observational cohort (no intervention applied) consisting of Beijing community-dwelling residents aged ≥60 years who meet the study's eligibility criteria (inclusion: able to cooperate with questionnaires; exclusion: severe mental illness, end-stage disease, or expected lifespan \<1 year). The cohort is established to prospectively track changes in urinary function (e.g., indicators of chronic kidney disease, overactive bladder, benign prostatic hyperplasia) and the occurrence/progression of multimorbidity (e.g., metabolic syndrome, cardiovascular diseases, diabetes) over time. It serves to analyze the dynamic association between age-related urinary function decline and multimorbidity, without implementing any experimental treatments or interventions-only collecting natural health data, biological samples, and follow-up outcomes (e.g., functional decline, disease diagnosis, death) as part of routine observation.