Urinary Leukotriene E4 Levels in Children With Obstructive Sleep Apnea

Eastern Virginia Medical School (EVMS)

Status: Completed

Conditions: Obstructive Sleep Apnea

Study type: Observational

Funder types: Other

Identifiers

NCT02205346

October 2013

Details and patient eligibility

About

Investigate urinary leukotriene E4 levels and determine if there is a correlation with severity of obstructive sleep apnea. The investigators then would like to determine a threshold level which could then be used for confirmation of diagnosis of obstructive sleep apnea (OSA).

Enrollment: 130 patients

Sex: All

Ages: 2 to 16 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• children 2-16 years of age
• scheduled for polysomnogram

Exclusion criteria

• cardiovascular, neuromuscular, immunologic or craniofacial disorders
• pharmacologic treatment including corticosteroids and leukotriene receptor antagonists in the last month
• subjects who have already received treatment for OSA with an oral appliance, continuous positive airway pressure (CPAP) device
• previously undergone tonsillectomy and/or adenoidectomy

Trial design

130 participants in 1 patient group

no treatment

Description:

no treatment