Urinary NGAL Acute Kidney Injury After Stored Red Blood Cells Transfusion in Critically Ill Patients.

Kasr El Aini Hospital

Status: Completed

Conditions: Anemia; Acute Kidney Injury

Treatments: Diagnostic Test: urinary NGAL

Study type: Observational

Funder types: Other

Identifiers

NCT03560921

KA-13115

Details and patient eligibility

About

The study aims to explore the association of the novel urinary bio marker NGAL with the age of PRBCs(packed red blood cells) transfusion in critically ill patients.

Full description

The investigators will measure the urinary NGAL in all patients who received blood transfusion in the intensive care unit during the study period. The age of PRBCs transfusion will be correlated with the incidence of AKI. The rise of NGAL and serum creatinine will be used to diagnose AKI (Acute Kidney Injury).

Enrollment: 147 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Any patients admitted to the intensive care unit.

Exclusion criteria

• patients who have established AKI at the time of recruitment

Trial design

147 participants in 2 patient groups

Stored blood transfusion

Description:

measurement of urinary NGAL

Treatment:

Diagnostic Test: urinary NGAL

Fresh blood transfusion

Description:

measurement of urinary NGAL

Treatment:

Diagnostic Test: urinary NGAL