Urinary Retention Following taTME VS laTME Total Mesorectal Excision for Rectal Cancer

Yanhong Deng

Status: Completed

Conditions: Rectal Cancer

Treatments: Procedure: Laparoscopic Total Mesorectal Excision; Procedure: transanal total mesorectal excision

Study type: Interventional

Funder types: Other

Identifiers

NCT06147492

GIH-SYip66

Details and patient eligibility

About

A comprehensive study with prospectively collected data. These patients were assigned to either the taTME group or the laTME group according to the surgery procedure received

Full description

Transanal total mesorectal excision has emerged as a potential solution to certain limitations associated with laparoscopic total mesorectal excision in rectal cancer patients. Differences in surgical approaches have raised questions regarding their impact on the risk of postoperative urinary retention, with limited data available from large scale study.

Enrollment: 526 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age range from 18 to 65 years,
• Diagnosed with rectal cancer at clinical tumor node metastasis stages II or III.
• Palpable tumor determined by digital rectal examination or proctoscopy
• The distal border of the tumor located within 12 cm from the anal verge

Exclusion criteria

• Patients presenting clear indications of pelvic side wall involvement or distant metastasis
• Uncontrolled hypertension or cardiovascular disease
• Patients with synchronous colon cancer
• History of other malignancies within the past 5 years

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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526 participants in 2 patient groups

laTME

Other group

Description:

Laparoscopic Total Mesorectal Excision

Treatment:

Procedure: Laparoscopic Total Mesorectal Excision

taTME

Other group

Description:

a transanal bottom-up approach was employed for the Total Mesorectal Excision procedure

Treatment:

Procedure: transanal total mesorectal excision

Procedure: Laparoscopic Total Mesorectal Excision