Urine Output Response to Fluid and Diuretic Therapy in Cardiac ICU Patients Monitored With FIZE kUO®

FIZE Medical ltd

Status: Not yet enrolling

Conditions: Postoperative Complications; Fluid Therapy; Cardiac Surgery; Hemodynamic Instability; AKI - Acute Kidney Injury

Treatments: Device: FIZE kUO®

Study type: Observational

Funder types: Industry

Identifiers

NCT07022314

FM-01

Details and patient eligibility

About

This prospective observational study evaluates the real-time urine output response to fluid therapy and diuretics in cardiothoracic intensive care unit (CTICU) patients monitored with the FIZE kUO® device. The study aims to assess how continuous urine output monitoring can inform fluid management and improve patient outcomes post-cardiac surgery.

Full description

The study involves adult patients undergoing coronary artery bypass graft (CABG) or valve replacement/repair surgeries. Utilizing the FIZE kUO® device, continuous urine output data will be collected to analyze responses to hemodynamic interventions, including fluid boluses and diuretics. Secondary objectives include assessing urine output differences in patients with and without postoperative acute kidney injury (AKI), responses to vasopressors, and capturing real-time urine output data from FIZE kUO® for observational analysis.

Enrollment: 45 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Adults aged 18 years and older scheduled for CABG or valve surgery and expected postoperative admission to CTICU
2. Ability to provide informed consent

Exclusion criteria

1. Pregnancy
2. Preoperative dialysis (chronic or acute)
3. Enrollment in other interventional trials assessing urine output or AKI

Trial design

45 participants in 1 patient group

Cardiothoracic ICU Patients

Description:

Adult patients (≥18 years old) undergoing coronary artery bypass graft (CABG) and/or valve surgery, admitted postoperatively to the Cardiothoracic Intensive Care Unit (CTICU), and connected to the FIZE kUO® device for real-time urine output monitoring as part of standard care.

Treatment:

Device: FIZE kUO®