Urine pH and Diet Net Acid Load

University of California San Francisco (UCSF)

Status: Withdrawn

Conditions: Healthy

Treatments: Other: high or low acid diet

Study type: Interventional

Funder types: Other

Identifiers

NCT02116595

UPH&DNAE

Details and patient eligibility

About

Presently, the gold standard for testing diet acid intake is a urine collection done for many hours, usually 24 hours, which must be analyzed in a research lab for "net acid excretion". So, getting information about diet acid intake is difficult. Many people have suggested doing a much simpler test, which is checking the pH of the urine when you wake up. But, no one has studied if this simpler method is a valid method for estimating the 24 hour net acid excretion. Diet acid load may be important in many diseases associated with aging, such as loss of bone and muscle, and the development of kidney disease.

Full description

the primary outcome variable is morning urine pH and 24 hour urine net acid excretion

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• no medical or psychological problems
• able to come to UCSF for study

Exclusion criteria

• pregnant or trying to become pregnant
• Hg < 10
• abnormal screening labs
• anyone unable to follow study directions

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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0 participants in 2 patient groups

feeding a high acid diet x 24 hrs

Experimental group

Description:

2 diets, one low and one high net acid loads

Treatment:

Other: high or low acid diet

low acid diet

Active Comparator group

Treatment:

Other: high or low acid diet