Usability of Virtual Reality in Subjects With Mild Cognitive Impairment or Alzheimer's Disease (MeMO-RV2)

Centre Hospitalier Universitaire de Nice

Status: Completed

Conditions: MCI; Alzheimer's Disease

Treatments: Other: Condition virtual reality (VR) then Condition classic cognitive stimulation (CCS); Other: Condition classic cognitive stimulation (CCS) then Condition virtual reality (VR)

Study type: Interventional

Funder types: Other

Identifiers

NCT02176629

14-PP-03

Details and patient eligibility

About

Cognitive and memory problems characterize Alzheimer's disease (AD). Along with these disorders, psychological and behavioral symptoms (also known as neuropsychiatric symptoms) , as well as pathophysiological processes are frequently found and involved significantly in maintaining autonomy, prognosis and treatment of the disease. Apathy or disorder motivation is the most common disorder behavior and early stages of cognitive impairment. Apathy is particularly associated with cognitive difficulties such as attention deficit disorder - concentration.

In terms of prevention as term care , there is now a broad consensus that interventions on cognition and behavior must not be limited to pharmacological treatment but should also promote non-drug approaches.

Interest in video games (serious games and serious games) as intervention support rehabilitation is growing. Similarly, the virtual reality (VR) and the new information technologies and communications offer significant opportunities in terms of rehabilitation and therapeutic assistance.

This protocol is part of a European project to propose techniques for improving the treatment of people at risk of social exclusion ( VERVE project ) aims .

A first experiment conducted in 2013 showed the acceptability of Virtual Reality (VR) in healthy elderly subjects. In a second step , it is important to validate the feasibility of using the RV or in frail subjects with mild cognitive impairment or Alzheimer's disease in mild to moderate in a clinical environment.

This is a biomedical , randomized given to a group of patients with mild cognitive impairment or Alzheimer's disease & diseases associated with mild to moderate.

Enrollment: 60 patients

Sex: All

Ages: 60+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Male or female age ≥ 60 years.

• Introducing either:

  • MCI diagnosis (ICD-10)
  • diagnosis of Alzheimer's disease or mixed mild to moderate (ICD 10).

• Subject undisturbed locomotion requiring the use of a walking aid.

• Score at the Mini Mental Test (MMSE) between 16 and 28.

Exclusion criteria

• Presence of psychiatric disorders
• Presence of eye diseases causing blurred vision can not be corrected with lenses or glasses.
• Presence of auditory pathologies causing a significant decrease in hearing unaided.
• High sensitivity to motion sickness.
• migraine disease.
• Subject epileptic.
• Subject vulnerable

Trial design

60 participants in 2 patient groups

Condition virtual reality (VR)

Experimental group

Description:

The subject is placed in front of a Barcotm screen capable of displaying high quality images.

Treatment:

Other: Condition virtual reality (VR) then Condition classic cognitive stimulation (CCS)

Condition classic cognitive stimulation (CSC)

Active Comparator group

Description:

It is proposed about using the test dam Zazzo suitable for elderly. This classic test measures sustained attention.

Treatment:

Other: Condition classic cognitive stimulation (CCS) then Condition virtual reality (VR)