Use of 2-octylcyanoacrylate (Dermabond) Versus 5-0 Fast Absorbing Gut During Cutaneous Wound Closure

University of California (UC) Davis

Status: Completed

Conditions: Wound Closure Techniques

Treatments: Procedure: Wound Closure with 2-octylcyanoacrylate; Procedure: Wound Closure with 5-0 Fast Absorbing Gut Sutures

Study type: Interventional

Funder types: Other

Identifiers

NCT02547077

774875

Details and patient eligibility

About

The purpose of this study is to determine whether the use of 2-octylcyanoacrylate during repair of linear cutaneous surgery wounds improves scar cosmesis compared to wound closure with 5-0 fast absorbing gut.

Full description

The purpose of this study is to determine whether the use of 2-octylcyanoacrylate during repair of linear cutaneous surgery wounds improves scar cosmesis compared to wound closure with 5-0 fast absorbing gut. The investigators will use a split wound model, where half of the wound is treated with 2-octylcyanoacrylate and the other half is repaired with 5-0 fast absorbing gut. Three-months post-surgery, the scar will be measured via the physician observer scar assessment scale, a validated scar instrument. The scar width, and adverse events will also be recorded.

Enrollment: 50 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 years of age or older
• Able to give informed consent themselves
• Patient scheduled for cutaneous surgical procedure with predicted linear closure of 3 cm of longer.
• Willing to return for follow-up visits

Exclusion criteria

• Mentally handicapped
• Unable to understand written and oral English
• Incarceration
• Under 18 years of age
• Pregnant Women
• Wounds with predicted closure length less than 3 cm

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

Wound Closure with 2-octylcyanoacrylate

Experimental group

Description:

One side of the patient's wound defect will be assigned to wound closure with 2-octylcyanoacrylate liquid bonding agent).

Treatment:

Procedure: Wound Closure with 5-0 Fast Absorbing Gut Sutures

Procedure: Wound Closure with 2-octylcyanoacrylate

Wound Closure with 5-0 Fast Absorbing Gut

Active Comparator group

Description:

One side of the patient's wound defect will be assigned to wound closure with 5-0 fast absorbing gut sutures.

Treatment:

Procedure: Wound Closure with 5-0 Fast Absorbing Gut Sutures

Procedure: Wound Closure with 2-octylcyanoacrylate