Use of Antibacterial Cement in Infected Dentin (AC)

University of Pernambuco

Status: Completed

Conditions: Dental Caries

Treatments: Other: Antibacterial cement

Study type: Interventional

Funder types: Other

Identifiers

NCT01449136

1535/07

Details and patient eligibility

About

Dental materials with antibacterial properties can prevent the harmful effects caused by oral cariogenic bacteria. This double-blind controlled clinical trial evaluated the performance of antibacterial cement for sealing infected dentin in atraumatic restorations of primary molars.

Full description

The study enrolled 45 children (45 teeth) between 5 and 8 years of age, of both genders, divided into two groups. In group A (GA; n=22), the cavities were lined with conventional glass ionomer cement (Vidrion F®) and in group B (GB; n=23), with antibacterial cement (Vidrion F® containing 1% each of metronidazole, ciprofloxacin, and cefaclor). Both groups were restored with Ketac Molar Easymix®. Molars with carious lesions on the inner half of dentin without clinical or radiographic pulp damage were selected. Patients were evaluated clinically (for pain, fistulas, or mobility) and radiographically (area of caries, periapical region, and furcation of teeth) after 1, 3, 6, and 12 months.

Enrollment: 45 patients

Sex: All

Ages: 5 to 8 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• signed consent from a parent or guardian;
• primary molars with carious lesions on the inner half of dentin;
• access of caries lesions to dentin spoons.

Exclusion criteria

• damaged pulp determined clinically (for pain, fistulas, tooth mobility);
• damaged pulp determined radiography (bone or dental pathology);
• children taking antibiotics;
• children who refused the treatment;
• children had systemic disease.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Double Blind

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45 participants in 1 patient group

antibacterial cement

Experimental group

Treatment:

Other: Antibacterial cement