Use of Antibiotic Carrier in Acute Periprosthetic Infections (APPI) of Total Knee Replacements

Michael Muldoon, M.D.

Status: Withdrawn

Conditions: Infection

Treatments: Procedure: APPI of TKR-Stimulan

Study type: Observational

Funder types: Other

Identifiers

NCT02107924

1112-0211

Details and patient eligibility

About

The purpose of the study is to gather information on the use of Stimulan, the surgery, and anitbiotics to whetether the APPI has decreased or shown improvement when compared to study participants who did not receive Stimulan during their revision total knee replacement surgery.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• APPI within 28 days of primary TKR
• Acute hematogenous infection within 4 weeks of symptoms

Exclusion criteria

• Exposed prosthesis
• Infection occuring in revised joints
• Poly articular infections
• have allergies to tobramycin or Vancomycin
• previous chronic infections in or around any ipsilateral extremity trauma or implants

Trial design

0 participants in 2 patient groups

APPI of TKR-Stimulan

Description:

Surgery Stimulan beads 2.4 G Tobramycin 2.0 G Vancomycin

Treatment:

Procedure: APPI of TKR-Stimulan

APPI of TKR-historical

Description:

Surgery 2.4 G Tobramycin 2.0 G Vancomycin