Use of Anticoagulant, and Associated Factors of Anticoagulant Refusal Atrial Fibrillation Patients

Prince of Wales Hospital

Status: Unknown

Conditions: Atrial Fibrillation

Treatments: Other: no intervention

Study type: Observational

Funder types: Other

Identifiers

NCT04062071

version1 last update 30/7/2019

Details and patient eligibility

About

Atrial fibrillation is a clinically significant cardiac arrhythmia that increases the risk of stroke by 3 to 4 times. Oral anticoagulation has been shown to mitigate stroke risk by two-thirds among patients with AF and is widely recommended in optimizing AF management.Direct oral anticoagulants have also been demonstrated to be superior to warfarin with respect to the risk of fatal bleeding and stroke prevention.

However, the previous study finding highlighted a great gap between current guidelines and the clinical management of AF .Nonetheless, the decision for anticoagulant use is not straightforward.It is worth to investigate the updated prevalence of anticoagulant use, the reasons for not receiving anticoagulant, and the factors independently associated with anticoagulant refusal in patients with non-valvular atrial fibrillation.

Enrollment: 300 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• diagnosis as atrial fibrillation
• aged ≧18 years
• able to given consent

Exclusion criteria

• Unable/unwillingness to sign informed consent to study
• mechanical heart valve
• moderate-to-severe mitral stenosis
• Transient atrial fibrillation from reversible cause (e.g., during respiratory tract infection or bronchospasm)
• pregnancy
• hospitalization within 1 month prior to inclusion in the study.