Use of Arimidex and Zoladex as Pretreatment to IVF in Women With Ovarian Endometriosis

Rigshospitalet

Status and phase: Completed; Phase 4

Conditions: Endometriosis

Treatments: Drug: Combined treatment with Arimidex and Zoladex before IVF

Study type: Interventional

Funder types: Other

Identifiers

NCT00286351

endo 220604

Details and patient eligibility

About

Does a combination of Arimidex and Zoladex make endometriomas shrink and how is the following IVF outcome

Sex: Female

Ages: 20 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Endometrioma(s)with a size of 20-70 mm, persisted for at least 3 cycles
• Couples with indication and wish for IVF/ICSI
• Age of women: 20-40 years
• Regular menstrual cycle within normal range (21-35 days)
• Body Mass Index (BMI): 18-30 kg/m2

Exclusion criteria

• History with osteoporosis, liver-, kidney- or heart disease or thromboembolic disease
• Treatment of endometriosis with GnRH agonist during the last 3 month

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)