Use of Blood Biomarkers and Biomarker Index to Aid in the Diagnosis of Obstructive Sleep Apnea (OSA)

Beckman Coulter

Status: Completed

Conditions: Obstructive Sleep Apnea

Treatments: Diagnostic Test: blood biomarker

Study type: Observational

Funder types: Industry

Identifiers

NCT03122483

SAB-03-15

Details and patient eligibility

About

This multicenter prospective trial will evaluate the association between obstructive sleep apnea (OSA) and blood biomarkers in a representative population of consecutively enrolled symptomatic patients with a clinical suspicion of OSA.

Enrollment: 250 patients

Sex: Male

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Written Informed Consent
• Male
• 18-70 years old
• Presentation with symptoms suggestive of obstructive sleep apnea
• Diagnostic sleep study
• Blood draw

Exclusion criteria

• Prior (within past year) or current therapy for sleep apnea
• Use of opioid pain medication, steroids or allopurinol (within past 30 days)
• Use of chronic anti-inflammatory drugs (within past 7 days)
• Active cancer under current treatment or monitoring

Trial design

250 participants in 2 patient groups

OSA

Description:

Blood biomarker results in subjects with obstructive sleep apnea.

Treatment:

Diagnostic Test: blood biomarker

Non-OSA

Description:

Blood biomarker results in subjects without obstructive sleep apnea

Treatment:

Diagnostic Test: blood biomarker