Use of Clonidine to Prevent Withdrawal Following Prolonged Dexmedetomidine Infusions

Joseph D. Tobias

Status: Completed

Conditions: Sedation

Treatments: Drug: Clonidine

Study type: Observational

Funder types: Other

Identifiers

NCT02404077

IRB15-00256

Details and patient eligibility

About

The investigators' clinical practice makes use of oral clonidine as a means of transitioning from intravenous dexmedetomidine following prolonged infusions (more than 3-5 days). Although this is common clinical practice, there is limited clinical data to demonstrate the efficacy of this technique and to provide clonidine dosing guidelines. The purpose of this study is to retrospectively review the investigators' experience with the use of oral clonidine to prevent withdrawal following the prolonged administration of dexmedetomidine.

Enrollment: 712 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who received clonidine during the transition from dexmedetomidine.

Exclusion criteria

• None

Trial design

712 participants in 1 patient group

Clonidine

Description:

Patients who received clonidine following prolonged dexmedetomidine infusions

Treatment:

Drug: Clonidine