Use of Discarded Surgery Human Tissue Specimens for Basic Science Research (HumTisRes)

Centre Hospitalier Universitaire, Amiens

Status: Enrolling

Conditions: Vascular Calcification; Osteoblast

Study type: Observational

Funder types: Other

Identifiers

NCT04753593

PI2021_843_0002

Details and patient eligibility

About

Although it is now established that calcification process result from the joint and coordinated action of different cell types, many areas of shadow remain regarding the spatio-temporal implementation of these events. Highlighting these processes requires additional research to consider new approaches to clinical management of patients with such conditions. It is in this context that the investigators need to use residual human tissue fragments resulting from surgery which are not intended to be used for clinical-biological management of patients. The use of these pseudonymised human tissues will allow the investigators to conduct in vitro cell culture experiences.

Enrollment: 200 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing surgery in the Cardiac Surgery and Orthopedic Surgery departments of the CHU Amiens-Picardie
• patients who will be beforehand informed
• patients who will not be opposed to this study.

Exclusion criteria

• HIV and hepatitis positive patients