Use of Heliox in the Management of Neonates With Meconium Aspiration Syndrome

Poznan University of Medical Sciences (PUMS)

Status: Completed

Conditions: Meconium Aspiration Syndrome

Treatments: Other: Heliox mechanical ventilation

Study type: Interventional

Funder types: Other

Identifiers

NCT01274845

503-02-02215338-22961-03550

Details and patient eligibility

About

The aim of the study: to assess the effect of short-term mechanical ventilation with heliox in newborns with meconium aspiration syndrome on vital signs, oxygenation, acid-base balance and respiratory function parameters.

Enrollment: 8 patients

Sex: All

Ages: Under 1 day old

Volunteers: No Healthy Volunteers

Inclusion criteria

• meconium aspiration syndrome diagnosed based on clinical and radiological findings,
• respiratory failure requiring mechanical ventilation

Exclusion criteria

• congenital malformations or congenital genetic syndromes,
• persistent pulmonary hypertension of the newborn (PPHN) requiring inhaled nitric oxide treatment

Trial design

8 participants in 1 patient group

Heliox

Other group

Treatment:

Other: Heliox mechanical ventilation