Use of Hyaluronic Acid Injection in Lateral Patellar Compression With Femoral Condylar Degenerative Changes After Arthroscopic Release

Hawler Medical University

Status: Completed

Conditions: Anterior Knee Pain Syndrome

Treatments: Device: Hyaluronic acid injection; Device: No injection of Hyaluronic acid

Study type: Interventional

Funder types: Other

Identifiers

NCT04134611

HMU/Sherwan6

Details and patient eligibility

About

Ninety patients are involved in this study, who underwent arthroscopic lateral patellar release for lateral patellar compression syndrome and they had patellofemoral degenerative lesion, which diagnoses by MRI preoperatively and proved by arthroscopic examination to be early stages of degenerative changes with no loss of articular surface. The patients were divided in to two groups (A and B). Group A (45 patients) were treated by local injection of Hyaluronic acid intraarticularly, and Group B (45 patients) were no injection intraarticular.

Full description

This study was done by one orthopedic surgeon in two hospitals. Ninety patients are involved in this study, who underwent arthroscopic lateral patellar release for lateral patellar compression syndrome and they had patellofemoral degenerative lesion, which diagnoses by MRI preoperatively and proved by arthroscopic examination to be early stages of degenerative changes with no loss of articular surface. The patients were divided in to two matched groups (A and B) regarding the age and gender; Group A (45 patients) were treated by local injection of Hyaluronic acid intraarticularly, 2 weeks after arthroscopy and were followed by VAS of knee pain for one year at (3) months, (6) months and (12) months, and Group B (45 patients) were no injection intraarticular. The study started on June (2017) and ends on March (2020). injection of Hyaluronic acid was used and followed in the same way. All patients presented with anterior knee pain which failed to respond to conservative treatment for 6 weeks or recurrent of symptoms after stopping of conservative treatment which involved changes of life style and NSAID. MRI done for all patients before operation.

Enrollment: 90 patients

Sex: All

Ages: 26 to 47 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Lateral patellar compression syndrome

Exclusion criteria

• Patellar instability.
• Smoking.
• Diabetes Mellitus.
• Previous knee surgery.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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90 participants in 2 patient groups

Knee arthroscopy with Hyaluronic acid injection

Active Comparator group

Description:

Those patients who received hyaluronic acid injection

Treatment:

Device: Hyaluronic acid injection

Knee arthroscopy without Hyaluronic acid injection

Active Comparator group

Description:

Knee arthroscopy who did not Hyaluronic acid injection

Treatment:

Device: No injection of Hyaluronic acid