Use of Incretins in Diabetic Patients

University of Pavia

Status: Completed

Conditions: Diabetes Mellitus, Type 2

Treatments: Drug: DPP-4 inhibitors

Study type: Observational

Funder types: Other

Identifiers

NCT03486964

P-20180016468

Details and patient eligibility

About

Observational, retrospective study, conducted in diabetic patients aimed to evaluate the effects on the glyco-metabolic control and on cardiovascular events of different DPP-4 inhibitors. Patients will be stratified in patients taking different DPP-4 in addition to sulfonylureas, biguanides, thiazolidinediones, insulin, compared to those in therapy with other hypoglycemic classes, such as sulphonylureas, biguanides, thiazolidinediones, insulin, alone or in combination, in primary and secondary prevention.

Enrollment: 2,234 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Type 2 diabetic patients
• On oral hypoglycemic agents ± basal insulin
• In primary and secondary prevention

Exclusion criteria

• Patients with a follow-up of less than 8 years

Trial design

2,234 participants in 2 patient groups

DPP-4 plus other therapies

Description:

Patients in therapy with DPP-4 inhibitors in addition to sulfonylureas and/or biguanides and/or thiazolidinediones and/or insulin

Treatment:

Drug: DPP-4 inhibitors

Other therapies

Description:

Patients in therapy with other hypoglycemic classes, such as sulphonylureas and/or biguanides and/or thiazolidinediones and/or insulin.