ClinicalTrials.Veeva

Menu

Use of Intrathecal Analgesia in Appendectomy

N

Nigde Omer Halisdemir University

Status

Completed

Conditions

Analgesia
Anesthesia

Treatments

Drug: 250 mcg alfentanil
Drug: 25 mcg fentanyl

Study type

Interventional

Funder types

Other

Identifiers

NCT04196946
2013/512

Details and patient eligibility

About

Acute appendicitis which is the most common cause of acute abdominal pain, is an acute inflammation of appendix vermiformis. Appendectomy operations can be performed as laparoscopic and open surgery. Addition of opioids to intrathecal local anesthetics to improve the quality of preoperative analgesia is an increasingly used method in recent years. The aim of this study is to compare bupivacaine-fentanyl and bupivacaine-alfentanil which are used intrathecally to create motor and sensory block. 50 volunteer patients who were diagnosed as appendicitis by laboratory tests and clinical diagnostic methods in general surgery clinic and classified as American Society of Anesthesiologists Classification I-II (ASA Class I-II) aged between 20-60 years scheduled for laparoscopic appendectomy operation, were included in this study. The patients were randomly assigned into two groups, Group I and Group II. Patients received spinal anesthesia with either 10 mg heavy bupivacaine (2 cc)+25 mcg fentanyl (0.5 cc) intrathecally (Group I, n=25) or 10 mg heavy bupivacaine (2 cc)+250 mcg alfentanil (0.5 cc) intrathecally (Group II, n=25).

Enrollment

50 patients

Sex

All

Ages

20 to 60 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Individuals who will undergo laparoscopic appendectomy operation and volunteer to participate in the study were included.

Exclusion criteria

  • Individuals who meet the criteria but are not volunteers
  • Previously underwent appendectomy

Trial design

Primary purpose

Supportive Care

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

50 participants in 2 patient groups

Group I
Experimental group
Description:
25 mcg fentanyl intrathecally
Treatment:
Drug: 25 mcg fentanyl
Group II
Experimental group
Description:
250 mcg alfentanil intrathecally
Treatment:
Drug: 250 mcg alfentanil

Trial contacts and locations

0

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems