Use of Lumbar Drain to Remove Clots in Patients Admitted to the Neuro-ICU After Subarachnoid Hemorrhage.

Odense University Hospital

Status: Unknown

Conditions: Subarachnoid Hemorrhage.

Treatments: Procedure: Lumbar drain; Procedure: Ventricular drain

Study type: Interventional

Funder types: Other

Identifiers

NCT01886521

37238

Details and patient eligibility

About

Recently, a clinical trial showed that the use of lumbar drains compared to ventricular drain in patients suffering from subarachnoid hemorrhage resulted in less delayed ischemic neurological deficits but failed to show a clinical benefit after 6 months. The underlying assumption was, that the cerebrospinal fluid (CSF) obtained from lumbar drains has a higher concentration of blood than CSF from lumbar drains. The investigators decided to test this assumption. In this study, the investigators will randomize patients to either placement of a ventricular or a lumbar drain and analyze the CSF drainage on a daily basis.

Enrollment: 20 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients admitted to the neuro-ICU with aneurysmal subarachnoid hemorrhage
• In need for CSF drainage based on clinical judgment

Exclusion criteria

• intraventricular clots
• intraparenchymal clots causing midline shift
• pregnancy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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20 participants in 2 patient groups

Lumbar drain group

Experimental group

Description:

Lumbar drain

Treatment:

Procedure: Lumbar drain

Ventricular drain

Active Comparator group

Description:

Ventricular drain

Treatment:

Procedure: Ventricular drain