Use of MgSO4 for Pain After Bariatric Surgery

Yeditepe University Hospital

Status: Completed

Conditions: Therapeutic Opioid Induced Constipation (Disorder)

Treatments: Drug: Magnesium

Study type: Interventional

Funder types: Other

Identifiers

NCT03355807

obesity (magnesium)

Details and patient eligibility

About

The purpose of this study was to investigate the effect of magnesium sulfate on pain management for pain after sleeve gastrectomy operation

Full description

The purpose of this study is to investigate the effect of magnesium sulfate on pain management for pain after sleeve gastrectomy operation.

Design: A prospective, randomized, controlled clinical study.

Setting: University hospital.

Participants: Eighty patients undergoing sleeve gastrectomy.

Measurements and Main Results: Visual analog scale for pain score, sedation score, mean arterial pressure, heart rate, and valid and invalid analgesic demand will record. Serum magnesium levels will determined at preoperative evaluation, postanesthesia care unit admission and at 24 hours. Side effects will also record.

Enrollment: 80 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18 to 65 year old individuals who underwent laparoscopic sleeve gastrectomy.

Exclusion criteria

• One or more of the following: cardio - vascular and respiratory diseases, drug and/or alcohol abuse, use of daily an algesia 24 hours before the surgery, renal failure, and liver dysfunction.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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80 participants in 2 patient groups

Group MgSO4

Experimental group

Description:

The magnesium group (group Mg, n _ 40) received an additional infusion of MgSO4 (30 mg/kg by bolus and 10 mg/kg/h by infusion for 24 hours)

Treatment:

Drug: Magnesium

Group Control

No Intervention group

Description:

the control group (group C, n _ 40) received the same amount of IV saline