Use of Oxygen Nebulizer for Preventing Post-operative Sore Throat (POST)

Prince of Songkla University

Status

Completed

Conditions

Pain, Postoperative

Treatments

Other: Oxygen

Study type

Interventional

Funder types

Other

Identifiers

NCT01763177

EC56-008-08-1-1

Details and patient eligibility

About

Rationale: Delivery dry gas during anesthesia is associated with post-operative sore throat (POST). Oxygen nebulizer therapy increases humidity to the airway, especially post-extubation.

Objective: To investigate the effect and complications of oxygen nebulizer therapy on POST.

Enrollment

1,036 patients

Sex

All

Ages

18 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age 18-75 years
Pre-operative Hb >10 g% or Hct > 30%
American Society of Anesthesiologist (ASA) class I-III
Elective surgery
General anesthesia with oroendotracheal tube using Macintosh laryngoscope
Not exposed to intraoperative nitrous oxide
Oxygen saturation at room air > 95% before induction and at arrival the PACU

Exclusion criteria

Cases needing ICU admission immediately post-operative
Conditioning requiring post-operative oxygen therapy e.g. heart disease, pregnancy, morbid obesity, cardiac and thoracic surgery
Patients' conditioning affecting to complication of nebulizer oxygen therapy e.g. pulmonary disease, bleomycin treatment
Patient's conditioning affecting POST assessment e.g. pre-operative using ventilator, recent upper respiratory tract infection (URI), recent lower respiratory tract infection and history of difficult airway
Surgical conditioning affecting POST e.g. airway surgery, oral surgery, esophageal and neck surgery