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Use of Prone Position Ventilation in Danish Patients With COVID-19 Induced Severe ARDS Treated With VV-ECMO

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Rigshospitalet

Status

Completed

Conditions

Adverse Event
Prone Position
COVID-19 Acute Respiratory Distress Syndrome
ARDS, Human
Extracorporeal Membrane Oxygenation

Treatments

Other: Prone position ventilation

Study type

Observational

Funder types

Other

Identifiers

NCT05693051
20049299-PPV

Details and patient eligibility

About

Prone position ventilation was used 220 times in 44 out of 68 patients with severe COVID-19 induced ARDS treated with VV-ECMO. PPV treated patients did not benefit from PPV and the incidence of PPV related adverse events was high

Full description

Purpose: To describe the use and effects of prone position ventilation (PPV) in patients with COVID-19 induced Adult Respiratory Distress Syndrome (ARDS), treated with Veno-Venous Extracorporeal membrane oxygenation (VV-ECMO).

Methods: Nationwide retrospective analysis of all COVID-19 patients in Denmark from March 2020 - December 2021with severe ARDS and need of VV-ECMO treatment. Data on the number of patients treated with PPV, number of PPV-events, timing, the time spent in prone position, physiological response types, adverse events and outcomes are reported.

Enrollment

68 patients

Sex

All

Ages

18 to 120 years old

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: patients with COVID-19 induced severe ARDS accepted for and treated with VV-ECMO in Denmark

Exclusion Criteria:

  • none

Trial contacts and locations

2

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Data sourced from clinicaltrials.gov

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