Use Quantitative Microradiography to Predict the Periprosthetic Bone Loss in Distal Femur After Total Knee Arthroplasty

National Taiwan University

Status: Unknown

Conditions: Periprosthetic Bone Loss in Total Knee Replacement

Treatments: Radiation: dual energy x-ray absorptiometry

Study type: Observational

Funder types: Other

Identifiers

NCT01618149

201204035RIB

Details and patient eligibility

About

The investigators hypothesized that the microarchitecture of bone influence the degree of periprosthetic bone loss after total knee arthroplasty surgery. The investigators collected the bone fragment at the distal femur while performing total knee replacement and take quantitative radiography analysis . Before and after the surgery(6 month ,12 month) , the investigators check the BMD at identical location of the distal femur by using dual energy absorptiometry. The investigators will use linear regression to evaluate the relationship between the microarchitecture and the degree of bone loss.

Enrollment: 50 estimated patients

Sex: Female

Ages: 50 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• severe knee osteoarthritis
• post menopausal women

Exclusion criteria

• immune disease
• end stage of renal disease who receive dialysis
• history of fracture at ipsilateral distal femur

Trial design

50 participants in 1 patient group

severe knee OA who are indicated for total knee arthroplasty

Description:

the woman who are indicated for TKR and are post menopausal will be recruited in this study. We will excluded the patients who had immune disease ,previous fracture of femur and end stage of renal disease

Treatment:

Radiation: dual energy x-ray absorptiometry