Usefulness of Exhaled NO in the Differential Diagnosis Acute Eosinophilic Pneumonia and Bacterial Pneumonia

Seoul National University

Status: Unknown

Conditions: Acute; Eosinophilic Pneumonia

Study type: Observational

Funder types: Other

Identifiers

NCT01152424

FeNO in AEP

Details and patient eligibility

About

Acute eosinophilic pneumonia (AEP) is diagnosed by cell count analysis of bronchoalveolar lavage fluid. However, the performance of bronchoscopy is not easy for patients with AEP, because they usually have hypoxia. Exhaled nitric oxide (FeNO) is usually elevated in the patients with eosinophilic inflammation such as asthma, but there is no previous studies FeNO in the patients with AEP. Investigators hypothesized that FeNO elevated significantly in patients with AEP, and FeNO can be used as non-invasive diagnostic method in patients who are clinically suspected with AEP, especially when the performance of bronchoscopy is difficult.

Enrollment: 50 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients who visited the study hospital with bilateral pneumonic infiltration.

Exclusion criteria

• Patients who do not agree with our study protocol

Trial design

50 participants in 2 patient groups

Acute eosinophilic pneumonia

Community acquired pneumonia