Usefulness Of Flospan As A Premedication For Colonoscopy

Ajou University School of Medicine

Status and phase: Unknown; Phase 4

Conditions: Colonoscopy

Treatments: Drug: Placebo; Drug: Cimetropium bromide; Drug: Phloroglucin; Procedure: Colonoscopy

Study type: Interventional

Funder types: Other

Identifiers

NCT01842932

AJIRB-MED-CT4-09-257

Details and patient eligibility

About

Usefulness of Flospan as a premedication for colonoscopy: A randomized double-blind controlled trial

Full description

Cimetropium bromide is premedication of colonoscopy. However, it is contraindication for some diseases; benign prostatic hyperplasia(BPH) or other obstructive uropathy, intestinal obstruction, pyloric stenosis, glaucoma, myasthenia gravis, megacolon, paralytic ileus. In this cases, Flospan (phloroglucin) is effective alternative drug. So our research was to compare the effects of these two drugs.

Enrollment: 260 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Recipient endoscopic diagnostic purposes.

Exclusion criteria

• If you currently pregnant, or of childbearing potential
• Previous abdominal surgery or bowel resection.
• If under 18 years of age
• If the last two days, the administration of anticholinergic

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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260 participants in 2 patient groups

Phloroglucin & Placebo

Experimental group

Description:

Phloroglucin 20ml before examination \& Placebo 1ml before examination

Treatment:

Procedure: Colonoscopy

Drug: Phloroglucin

Drug: Placebo

Cimetropium bromide & Placebo

Experimental group

Description:

Cimetropium bromide 1ml before examination \& Placebo 20ml before examination

Treatment:

Procedure: Colonoscopy

Drug: Cimetropium bromide

Drug: Placebo