Usefulness of Neutrophil Gelatinase-associated Lipocalin(NGAL) to Confirm Acute Kidney Function Decrease of the Patients Who Had Non-cardiac Surgery

Inje University

Status

Completed

Conditions

Chronic Kidney Disease

Treatments

Other: The level of NGAL after pre op,post op 4hr, post op 12hr

Study type

Observational

Funder types

Other

Identifiers

NCT02233010

postOPNGAL01

Details and patient eligibility

About

Although post-op renal function decrease is determined by serum creatinine, serum creatinine has disadvantages that it increases a long time after renal function decrease and it has various increasing time based on the level of renal function. Neutrophil Gelatinase-associated Lipocalin (NGAL's) usefulness as an evidence for acute kidney damage occurring from post-op cardiac surgery, being critical patients and contrast medium use is already proven.

But NGAL's usefulness for renal function after non-cardiac surgery is not proven and especially, NGAL's usefulness for renal injury after non-cardiac surgery in chronic renal disease patients is not proven.Therefore, the investigators will study about renal function decrease after non-cardiac surgery with NGAL and serum creatinine.

Enrollment

43 patients

Sex

All

Ages

18 to 79 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

43 patients who had non-cardiac surgery in Seoul Paik Hospital.

Exclusion criteria

have viral hepatitis and Aspartate aminotransferase, Alanine aminotransferase > 2 time of normal level
severe lung disease
severe heart failure ( Ejection Fraction < 40% )
pregnancy