Usefulness of Video-Based Intervention in Helping Participants Encourage Their Families to Get Tested for BRCA Gene Mutations

The Ohio State University

Status: Active, not recruiting

Conditions: BRCA2 Gene Mutation; BRCA1 Gene Mutation

Treatments: Other: Informational Intervention; Other: Survey Administration

Study type: Interventional

Funder types: Other

Identifiers

NCT05264532

OSU-17312

NCI-2018-00756 (Registry Identifier)

Details and patient eligibility

About

This trial studies how well a video-based intervention works in helping participants encourage their families to get tested for BRCA gene mutations. Testing in families with BRCA gene mutations can allow for risk management and reduction with the overall goal of reducing cancer burden. Video-based intervention sent via text messages may help participants easily share information about BRCA gene mutations with family members.

Full description

PRIMARY OBJECTIVES:

I. To understand whether the use of a video-based message to encourage cascade testing, delivered via short message service (SMS) (text message) or shared on social media, is superior to a written message as a method of information-sharing among families that have BRCA gene mutations.

OUTLINE: Participants are randomized to 1 of 2 arms.

ARM A: Participants receive a 2-minute information-graphic video via text message consisting of misconceptions and issues that may be paramount when discussing mutation status with relatives that they can share with family via text message, email, or social media.

ARM B: Participants receive family letter via U.S. postal service mail consisting of misconceptions and issues that may be paramount when discussing mutation status with relatives.

Enrollment: 58 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Individuals who test positive for mutations in BRCA1 or BRCA2 are eligible for this study
• Family members who receive the video message/family letter will be invited to participate

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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58 participants in 2 patient groups

Arm A (video via text message)

Experimental group

Description:

Participants receive a 2-minute information-graphic video via text message consisting of misconceptions and issues that may be paramount when discussing mutation status with relatives that they can share with family via text message, email, or social media.

Treatment:

Other: Survey Administration

Other: Informational Intervention

Other: Informational Intervention

Arm B (letter via standard U.S. mail)

Active Comparator group

Description:

Participants receive family letter via U.S. postal service mail consisting of misconceptions and issues that may be paramount when discussing mutation status with relatives.

Treatment:

Other: Survey Administration

Other: Informational Intervention

Other: Informational Intervention