Uses of Irradiated Human Amniotic Membrane in the Treatment of Dystrophic Epidermolysis Bullosa Patients

Egyptian Atomic Energy Authority

Status: Completed

Conditions: Chronic Skin Ulcer; Epidermolysis Bullosa

Treatments: Biological: REGE pro dressing

Study type: Interventional

Funder types: Other

Identifiers

NCT03942250

2222018NCRRT

Details and patient eligibility

About

To evaluate the effect of human amniotic membrane as a weekly dressing on chronic wounds in Epidermolysis Bullosa (EB) patients.

Full description

Dried human amniotic membrane dressing were obtained from National center for radiation research and technology, Egypt (NCRRT), under commercial name REGE pro.

Enrollment: 8 patients

Sex: All

Ages: 12 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1- Patients diagnosed as EB wounds must be chronic

Exclusion criteria

1. Patients Must stop other line of treatment

2. Exclude patients have:

   1. Autoimmune diseases
   2. Diabetes

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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8 participants in 1 patient group

Treated

Experimental group

Description:

Patients who received REGE pro dressing on EB wounds lesion weekly for 10 weeks

Treatment:

Biological: REGE pro dressing