Using Adhesive Biosensor Patches to Characterize the Biochemical Phenotype in PTSD

Nadav Goldental

Status: Unknown

Conditions: Post Traumatic Stress Disorder

Study type: Observational

Funder types: Other

Identifiers

NCT04071132

6381-19-SMC

Details and patient eligibility

About

A psychiatric diagnosis of post-traumatic stress disorder (PTSD) is currently based mainly on non-quantitative elements, such as interviews and subjective impressions. PTSD has physiological manifestations, some of which are likely reflected in the levels and ratios of certain stress-related proteins in the interstitial fluid and plasma. Discernable patterns of such stress-related proteins may constitute a biochemical phenotype characteristic of PTSD, which may serve as a biomarker and support diagnostic decisions, as well as personalized treatment plans.

The current study is a non-interventional observational study aimed at examining the possibility of basing a psychiatric diagnosis by measuring changes in the biochemical phenotype of participants with PTSD.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 100 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• PTSD diagnosis (excluding controls)
• Proper ability to give informed consent

Exclusion criteria

• Active psychotic or suicidal symptoms
• Active/terminal oncological condition
• Dialysis patients
• Pregnancy

Trial design

50 participants in 2 patient groups

Participants diagnosed with PTSD

Non-PTSD participants