Using Artificial Intelligence-based ChatBot to Improve Women's Participation to Cervical Cancer Screening Programme (AppDate-You)

International Agency for Research on Cancer

Status: Begins enrollment in 1 month

Conditions: Cervical Cancer Screening; Cervical Cancer

Treatments: Behavioral: Decision aid tailored to women with lower educational attainment,accessible via artificial intelligence-based Chatbot platforms

Study type: Interventional

Funder types: Other

Identifiers

NCT05286034

IEC 21-16

Details and patient eligibility

About

This project looks to improve the return rate of HPV self-sampling (HPVss) as well as the management of women HPVss positive.

Full description

France has already implemented a cervical screening programme based on HPV test for the whole female population aged 30-65 years. Non-participant women can perform HPV test at their home. However, less than 20% of French women performed vaginal self-sampling when a kit was sent to their home. Women with lower income and educational levels participate less to cervical screening. A variety of personal, practitioner, test-related and logistical barriers negatively impact the screening participation of French women. Key barriers to participation could be addressed by overcoming disparities in HPV-related knowledge and perceptions about cervical cancer screening. This study aims to evaluate the impact of sending HPV self-sampling kit at women's home, associated with providing, through multiple mobile channels, a multi-language decision aid designed for women with lower education accessible via artificial intelligence-based ChatBot. This decision aid will help women review high quality evidence on cervical cancer disease and screening modalities.

Enrollment: 3,000 estimated patients

Sex: Female

Ages: 30 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria: eligible women will be:

• aged 30-65
• did not perform a pap smear in the last 4 years
• are living in deprived clusters in the Occitanie region.
• did not answer to a first "invitation" letter to perform a clinician-collected HPV testing

Exclusion criteria: ineligible women will be those:

• outside the target age group
• had a Pap smear in the past 3 years
• had hysterectomy including cervix
• are pregnant
• already scheduled a screening appointment or had just attended a HPV screening
• had a cervical abnormality that was under exploration and/or treatment.
• participated to the study pilot

Trial design

Primary purpose: Screening

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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3,000 participants in 2 patient groups

Intervention group

Experimental group

Description:

Women randomized to this group will be sent screening reminder letters to perform HPV self-sampling test, with access to a decision aid tool tailored to those with low education levels. This tool will be available via Chatbot platforms.

Treatment:

Behavioral: Decision aid tailored to women with lower educational attainment,accessible via artificial intelligence-based Chatbot platforms

Control group

No Intervention group

Description:

Women randomized to this group will be sent screening reminder letters to perform HPV self-sampling test (Standard care)