Using Combination of Synthetic Bone Substitutes During Extractions

Rambam Health Care Campus

Status and phase: Unknown; Phase 3

Conditions: Alveolar Bone Losses; Periodontitis; Dental Caries

Treatments: Device: Calcium Phosphate, Calcium Sulphate

Study type: Interventional

Funder types: Other

Identifiers

NCT01503593

0326-11-RMB

0362-11-RMB

Details and patient eligibility

About

The study was designed to assess the effectiveness of conservation ridge preservation (horizontal and vertical dimension) after tooth extraction with and without combination of bone substitutes based on synthetic (calcium sulfate mixed with phosphate.

Full description

Using the combination of these two bone substitute is taken in order to diminish the alveolar ridge alternations after tooth extraction. the investigator will measure the horizontal and vertical changes (primary outcome) and the adverse effects (secondary outcome)in 4 months period

Enrollment: 40 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients over age 18.
2. Patients who require extraction of teeth for Periodontal or other dental reasons (up one tooth in each quarter when there are existing adjacent teeth).

Exclusion criteria

1. Inability to pass informed consent procedure
2. Pregnant women
3. Breastfeeding women
4. Patient taking medications that affect bone metabolism such as bisphosphonates
5. Extractions sites contaminated
6. Smoking over 10 cigarettes a day
7. Patients with removable prostheses

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

Alveolar ridge dimensions

No Intervention group

Description:

Control group - Only extraction teeth

Alverolar ridge dimension

Experimental group

Description:

Extraction of teeth and implant a bone substitute

Treatment:

Device: Calcium Phosphate, Calcium Sulphate