Using Positive Pressure Ventilation for Preoxygenation During Panendoscopy. (PANNIV)

Centre Hospitalier Universitaire, Amiens

Status: Completed

Conditions: ENT Cancer Screening

Treatments: Device: positive pressure ventilation; Procedure: Oxygenation with simple breathing mask

Study type: Interventional

Funder types: Other

Identifiers

NCT02167334

2012-A01053-40 (Other Identifier)

PI12-DR-DIMOV

Details and patient eligibility

About

the aim of the study is to determine if Spontaneous Ventilation with Positive Pressure Ventilation (PPV) preoxygenation allows a longer non hypoxemic apnea time during panendoscopy compared to spontaneous breathing preoxygenation.

the hypothesis is PPV extends the residual functional capacity of lung so it provides more oxygen during apnea.

Enrollment: 50 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patient going for scheduled panendoscopy under general anesthesia

Exclusion criteria

• BMI upper to 35 kg/m2
• pregnancy
• requirement of jet ventilation
• tracheostomy
• acute respiratory failure: pneumonia, pulmonary embolism
• health insurance careless

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

positive pressure ventilation

Experimental group

Description:

Positive Pressure Ventilation with a 4 cmH2O inhale pressure, a positive end-expiratory pressure of 4 cm H2O, a trigger 2, an inspiratory slope of 0, an inhaled oxygen fraction of 100% administered at a 10 L / min flow.

Treatment:

Device: positive pressure ventilation

Oxygenation with simple breathing mask

Active Comparator group

Description:

spontaneously breathing preoxygenation with adapted face mask, to restrict leakage, at 10L/min oxygen, with inhaled fraction of 100% and a 2 L balloon volume.

Treatment:

Procedure: Oxygenation with simple breathing mask