Using Rapid Cine-MRI for Monitoring Moving and Deforming Tumors

The University of Texas System (UT)

Status

Terminated

Conditions

Lung Cancer

Treatments

Other: cine MRI

Study type

Interventional

Funder types

Other

Identifiers

NCT01421784

STU 042011-034

Details and patient eligibility

About

In this study, the researchers investigate the feasibility of using rapid cine MR imaging to provide both offline and online soft-tissue-based image guidance. Such images will provide a significantly more complete picture of the spatial and temporal changes in thoracic anatomy. This more complete information will lay the groundwork for better radiotherapy planning and dose delivery in the presence of respiratory motion.

Full description

Rapid MRI scans from Stage I-IV non-small-cell lung cancer (NSCLC) patients will be acquired. MR acquisition will be performed without extrinsically administered contrast, using a balanced turbo field echo (TFE) sequence and commercially available coils.

Enrollment

17 patients

Sex

All

Ages

18 to 99 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

AJCC Stage I, II, III or IV non-small-cell lung cancer to be treated using radiotherapy will be eligible for this study.
Any types and amounts of prior therapy will be allowed for this study.
Subjects must be greater than or equal to 18 years of age. There are no gender or ethnic restrictions.
Ability to understand and the willingness to sign a written informed consent document.
Able to tolerate supine position
ECOG performance status of 3 or less

Exclusion criteria

MRI-incompatible metallic implants, embedded metallic objects, implanted biomedical devices e.g., cardiac pacemakers
Women who are pregnant or trying to get pregnant
Pain in supine position