Using Teleneuropsychology to Optimize Cognition in Healthy Aging: the Web-based Breakfast Game

Columbia University

Status: Completed

Conditions: Healthy Aging

Treatments: Behavioral: Web-based regular training (no strategy); Behavioral: Web-based training strategy

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT05506852

1K99AG078561-01 (U.S. NIH Grant/Contract)

AAAT4773

Details and patient eligibility

About

Executive control processes involve initiate, coordinate, synchronize, and regulate elemental cognitive functions for the conduct of goal-directed behavior. The proposed research investigates whether exposure to a web-based training protocol designed to enhance executive control processes will improve cognitive performance in cognitively healthy older adults.

Full description

The proposed research investigates whether exposure to a web-based training protocol designed to enhance executive control / multi-tasking abilities will improve cognitive performance in healthy older adults. Cognitively normal adults aged 60-75 will be randomized into two experimental groups: 1) Web-based game with training strategy; 2) Web-based game without training strategy (Active Control). All participants (groups 1 and 2) will be instructed to play the complex, high-demand online game, Breakfast Game, for 14 one-hour sessions over 5 weeks.

Enrollment: 38 patients

Sex: All

Ages: 60 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age 60-75
• Willingness to adhere to training protocol
• Adequate English proficiency

Exclusion criteria

• Low test scores (below 26 on the Montreal Cognitive Assessment)
• Known history of cognitive impairment, dementia, stroke, seizure disorder, or other neuropsychiatric condition judged to impact cognitive performance.
• Taking medications known to influence cognitive performance.
• Sensory (e.g. visual, auditory) or physical (e.g. severe arthritic, orthopedic, neurologic) impairment incompatible with use of a standard computer workstation.
• Enrolled in a concurrent study that could affect the outcome of this study.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

38 participants in 2 patient groups

Strategy Training

Experimental group

Description:

Participants will play the Breakfast Game with training strategy.

Treatment:

Behavioral: Web-based training strategy

Regular Approach

Active Comparator group

Description:

Participants will play the Breakfast Game without training strategy.

Treatment:

Behavioral: Web-based regular training (no strategy)