Using Three Different Final Irrigants and Showing Their Effects on the Success of Revascularization

Cairo University (CU)

Status: Unknown

Conditions: Post-operative Pain

Treatments: Drug: Propolis; Drug: Nano-propolis; Drug: saline

Study type: Interventional

Funder types: Other

Identifiers

NCT03591172

CEBD_CU_2018_05_29

Details and patient eligibility

About

this study will assess different irrigating materials on the success revascularization of necrotic mature teeth associated with PRF.

Full description

Nano-propolis and Propolis will be used as final endodontic irrigants and will be compared to saline in Revascularization of necrotic mature teeth.

Enrollment: 75 estimated patients

Sex: All

Ages: 15 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• mature teeth.
• teeth with periapical periodontitis.
• Maxillary anterior teeth
• Patients should be free from any systemic disease
• Patients who will agree to the consent and will commit to follow-up period.

Exclusion criteria

• Patients with immature roots.
• Patients with any systemic disease that may affect normal healing.
• Patients with swelling. .Pregnant females. .Patients who could/would not participate in a 1-year follow-up. .Patients with fistula. .Patients with old age. .Teeth with periodontal involvement. .Teeth with vertical root fractures. .Non-restorable teeth.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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75 participants in 3 patient groups

propolis

Experimental group

Description:

natural antibacterial, anti-inflammatory irrigation solution

Treatment:

Drug: Propolis

Nano-propolis

Experimental group

Description:

natural antibacterial, anti-inflammatory irrigation solution

Treatment:

Drug: Nano-propolis

saline

Active Comparator group

Description:

sodium chloride irrigation solution

Treatment:

Drug: saline