Utah Study Evaluating Apneic Oxygenation for Emergency Department Intubation (USE AP OX)

Intermountain Health Care, Inc.

Status: Unknown

Conditions: Intubation

Treatments: Other: Apneic oxygenation; Other: Pre-oxgenation with NRB, NIPPV, BVM

Study type: Interventional

Funder types: Other

Identifiers

NCT02961933

1050200

Details and patient eligibility

About

This study will determine rates of first pass success without hypoxemia in emergency department intubations with and without the use of apneic oxygenation by nasal cannula.

Enrollment: 500 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients requiring emergent Rapid Sequence or Delayed Sequence endotracheal intubation with administration of a neuromuscular blocker (Succinylcholine, Rocuronium)

Exclusion criteria

• Known prisoners
• Patients in cardiac arrest
• Patients who are intubated without the use of neuromuscular blockade (i.e., cardiac arrest, awake intubation).

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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500 participants in 2 patient groups

Apneic oxygenation

Experimental group

Treatment:

Other: Apneic oxygenation

non-apneic oxygenation

Active Comparator group

Treatment:

Other: Pre-oxgenation with NRB, NIPPV, BVM